Skip links

IV Ketamine Therapy.

What is Ketamine therapy?

Ketamine is an anesthetic medication that’s been FDA-approved for use in surgery since the 1970s. But pain relief is far from its only advantage. An ever-growing body of scientific research has proven that low-dose intravenous (IV) ketamine infusions can also have transformative effects on the brain that effectively “reboot” it to treat various mental health conditions including treatment-resistant depression, anxiety, and more.

Discover more about Ketamine in our FAQ’s

How does ketamine work?

Traditional antidepressants work by blocking the reabsorption of brain chemicals like serotonin, norepinephrine, and dopamine to improve communication between brain cells. Ketamine, on the other hand, acts on a wide number of receptors in the brain. This multilayered effect creates ideal conditions for a “reboot,” resetting the mind’s innate ability to heal itself.

One part of the brain that ketamine targets is the most common neurotransmitter, glutamate. At low doses, ketamine boosts production of glutamate and BDNF, a vital protein. When this happens, some people may have vibrant daydreams or a magical feeling of the mind separating from the body. But throughout this transcendent experience, ketamine is working hard to build new, stronger, healthier connections, or synapses, between brain cells.

This is exciting for its potential to revolutionize how we treat many common mental health issues. More and more of us in modern life exist in an always stressed state, and chronic stress depletes essential neurotransmitters in parts of the brain linked with depression and other mental health conditions. Ketamine can reverse that process and the symptoms that come with it—effectively rebooting the brain and reacquainting patients with their foundation, values, and intentions. At low doses, ketamine also relaxes the mind and gives it a break from cyclical thoughts and stories.

The manner in which the brain perceives this transformation can sometimes manifest in unusual or surprising ways. You may have an “out-of-body experience” or feel like you are “floating” as you reflect from deep within your body and life. This is important because to some degree it parallels the intensity of the effect ketamine achieves at the molecular level. Dr. Herman will adjust the amount of ketamine your brain sees from session to session, SLOWLY, in order to maximize its effects and minimize the potential for unpleasant experiences.

Your preparation and mindset will also be very important. Your open mind will allow you to embrace these experiences and use them as a transformative tool.

How Does It Feel to Get Ketamine Therapy?

What can I expect when I get an infusion?

Dr. Herman will be there to make sure you are safe at all times. She will also curate the perfect setting that resonates with you to help make the rebooting period as comfortable as possible, hopefully even exciting and pleasurable. Music can serve as a reassuring presence along the journey. Soft Reboot offers an immersive deep listening experience that can be tailored to your preference or treatment intention, for example, gentle/peaceful/grounding or a sadness release. You also could decide that you prefer guided meditation during the session. The choice is yours.

It is important to know in advance that most clients actually do not start to feel better before the end of their first treatment, or even on the same day. For the first four to six hours after the infusion session you may feel anxious that nothing is happening. You may also have a lingering unpleasant headache, mild dizziness, or nausea. Just know that despite these physical sensations, the ketamine is starting to work on the growth of depression-stunted neurons and synapses in the brain.

Instead, it is usually 24 to 72 hours after an infusion session when clients, and even their family and friends, will notice a change, i.e. increased energy, whistling and/or smiling, making jokes, or just a more optimistic overall demeanor. Think of the next two to three days as your window of opportunity to make new breakthroughs in therapy. Also invite the opportunity to explore further with meditation or breathwork. Further, clinically noticeable effects are cumulative; several sessions will result in a more consistent and longer lasting effect.
Soft Reboot Wellness can partner with your existing mental health care provider to tailor the experience to your goals and facilitate ketamine-assisted psychotherapy. If you don’t already have a provider, we’ll invite our in-house specialist to meet with you and offer guidance.

We will monitor your post-infusion course by tracking your mood in between sessions with Osmind. This will allow us to follow your response and progress after each infusion. As part of the app, you can send Dr. Herman secure messages directly, journal to help with reflection and integration, and join the Osmind community in order to connect with others on their own ketamine journeys.

We will continue the next infusion where the prior left off. And so on. The initial series is usually six infusions over two to three weeks. Because this is a personal journey, we will customize the number of initial infusions based on how you respond and any feedback that your trusted mental health provider may offer. We emphasize a team approach in individualizing patient care.

After the initial series, reduction in depressive symptoms lasts approximately five weeks, with a range of 3 weeks to 2 months noted for most people. Subsequent single maintenance (or “booster”) infusions may be necessary to sustain symptom improvement. Each client is unique; these boosters may be indicated anytime from three weeks to three months after the initial series.

Is ketamine safe?

Ketamine has been proven safe and effective over decades of widespread use. The drug has a minimal effect on breathing, blood pressure, or heart rate, making it an ideal anesthetic. It was first FDA-approved for anesthesia in 1970. The amount given during an infusion for mental health treatment is just a fraction of the dose safely used in sedation during surgery. But ketamine’s mental health applications are still considered “off-label” uses of the drug, meaning they are emerging treatments that the FDA hasn’t yet formally approved. Research on ketamine for depression and other mental health conditions is extensive and ongoing. It should always be given in a monitored setting by a licensed physician or medical professional trained specifically in ketamine administration.

While the medication is extremely safe, there are recommended standards for administration. Therapy should be done by a licensed physician who can administer a DEA schedule III medication. ACLS certification is recommended as well as meeting the American Society of Anesthesiologists’ requirements for the delivery of moderate sedation. It is also recommended that the outpatient environment where these services are performed have the ability to monitor vitals. Additionally, when patients have a pre-existing history of cardiovascular or respiratory problems, they may receive additional support and monitoring with oxygen therapy and continuous end-tidal CO2 monitoring during their infusions.
All of our treatments are administered and monitored by our founder, Harvard-trained board-certified anesthesiologist, Dr. Sara Herman. Dr. Herman has over 12 years of experience administering ketamine in operating room settings. She personally provides all clinical services related to the administration and monitoring of every client in her office. Each client is monitored safely and according to the above practice guideline and concordant with the medical records and information provided by the client.

Can ketamine help me?

We partner with your existing treatment team to truly integrate and tailor our care to your individual needs. Ketamine can help with…

Treatment-resistant depression

Treatment-resistant anxiety



Postpartum mental health

Premenstrual dysphoric disorder (PMDD)


Personal/spiritual growth

Chronic pain



Discover what you can expect on your journey.

Ketamine Therapy Pricing

Ketamine is a powerful, paradigm-shifting tool. However, it is NOT intended as a one-time treatment or cure. Research published in The American Journal of Psychiatry shows IV ketamine treatments are most effective in an induction series of six infusions within a two-to-three-week period. When you’re ready to commit to transformation, we recommend this approach.

We charge an initial consultation fee of $400 that goes toward the first treatment. The first session ($750/infusion) includes a Mindfold eye shade, personal Caretaker simple finger sensor, a one month free membership to, and free Osmind access and online support community.

What to expect on your Journey

When you feel called to the path toward transformation, we’re here, waiting to escort you on the journey.

Do you offer ketamine therapy for depression in the Bay Area?

Suffering from depression can take a toll on your mental state.   Soft Reboot Wellness can help and provide ketamine to treat your depression.

Ketamine Science & Resources

Can Psychedelics Make You Less Depressed? | The War on Drugs

Revealing the Mind: The Promise of Psychedelics

Psychedelic Drugs Are Fueling a Mental Health Revolution

How to Change Your Mind

How Are Psychedelics and Other Party Drugs Changing Psychiatry?

Neuroplasticity and the next wave of antidepressant strategies

Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories

Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression...

A Randomized Add-on Trial of an N-methyl-d-aspartate Antagonist in Treat...

Call Us